Beyond viability

Why preserving functional performance of T-cells is essential

New white paper

Pentahibe Complete
- the high-performance cryopreservation solution for advanced immunotherapy

Cryopreservation performance is often assessed by post-thaw viability. While this provides a useful starting point, it does not fully capture how well T-cells retain their functional properties after thaw. This places particular importance on how cryopreservation conditions are defined and characterized during development.

Download the white paper today to learn more about how Pentahibe Complete preserves viability, recovery and functional immune response – with 80% less DMSO.*

Download white paper

Why Pentahibe

Pentahibe® protects and preserves cells during cryopreservation without compromising functionality with its natural extracellular carbohydrate-based cryoprotective agent, pentaisomaltose.

PentaHibe Complete is designed to deliver:

Enhanced
safety

Pentahibe Complete, containing 2% DMSO, minimises cellular toxicity and DMSO-related side effects.1

Improved
outcomes

Pentahibe Complete, with just 2% DMSO, shows comparable results to commercially available cryosolutions with higher DMSO concentrations and demostrates superior migratory potential.2,3

Tested on
multiple cell types

Pentahibe Complete, cGMP manufactured, has been tested on T-cells, human mesenchymal stem cells, and CHO cells and comes with comprehensive documentation for regulatory submissions.

Safe alternatives exists today and we are committed to moving the field toward a future where cryopreservation is both safe and effective - without compromise.

Learn more about Pentahibe Complete

PentahibeComplete

Read more

  • Ready-to-use formula

  • 10% pentaisomaltose, a non-penetrating carbohydrate-based CPA

  • 2% DMSO

* PentaHibe Complete (with 2% DMSO) vs a commercial cryopreservation product containing 10% DMSO.

1. Svalgaard JD et al. Cell Transplantation, 2018 Sept; Vol 27(9): 1407-1412.

2. Haastrup EW et al. Transplantation and Vpheresis Science, 2021; Vol 60(4): 103138.

3. Svalgaard JD et al. Cryobiology, 2020; Vol 96(01): 207-213.

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